After gathering virtually last year, the APE Conference returns to a physical meeting in Berlin in January 2022. As usual, the APE 2022 Program Committee has put together a varied and substantial Provisional Program which offers 40+ expert speakers on a wide array of topics. The main theme is the Future of the Permanent Record. Topics include building a framework for the future of the record of science, metadata quality and trustworthiness, threats to the version of record by papermills and other sources and ensuring public access to research data. Further highlights include a panel discussion with key tech entrepreneurs from Mendeley, ResearchGate and Morressier as well as the always popular “Dotcoms to watch”. Online participation options will also be included.